MLL-MLL

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Research Focus

Structural rearrangements involving the MLL gene at 11q23 are common recurring abnormalities in de novo and therapy-related hematologic disorders. MLL rearrangement most often results from translocation or partial tandem duplication.

Target Disease/Application

Childhood acute lymphoblastic leukemia

Chromosomal Alteration

dupMLL (11q23)

Assay ID Clinical Name Gene Symbol Gene Aliases Amplicon Length  
Hs03043624_ft MLL e6-e2/e7-e2 MLL-MLL MLL 111

Specifications

General Specifications

# of assays: 1
Technology: TaqMan® Assays - Pre-formulated assay (20x or 60x mix)
Scale: Available in multiple scales
Intended Use: Research Use Only

Kit Storage

-20° C

Documents

Product Literature

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Citations & References (1)

  • Prospective application of a multiplex reverse transcription-polymerase chain reaction assay for the detection of balanced translocations in leukaemia: a single-laboratory study of 390 paediatric and adult patients.

Authors
Olesen LH et al.
Journal
Br J Haematol. 2004 Oct;127(1):59-66.
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